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Safe and effective vaccine against Clostridium perfringens in poultry

The vaccine consists of a combination of recombinant NetB and alpha-toxin, both detoxified. C. perfringens infections in poultry may present as an acute clinical disease, with high mortality at 2 to 5 weeks of age, or in a subclinical form leading to reduced weight gain which costs the worldwide poultry industry 2 billion USD annually (or 0,05USD per bird) Proof of concept in target species (Ross308 broilers) Immunisation with NetB- and alpha-toxoid reduced lesion scores completely. None of the animals vaccinated with a combination of NetB and CPA developed necrotic enteritis lesions after challenge.

A recombinant vaccine based on toxoids of NetB and alfatox fit for vaccination of chickens against Clostridium perfringens.

Sven Arnouts
sven.arnouts@ugent.be
+32 495 707 334

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Una iniciativa de

Ayuda PTR2022-001249 financiada por:

UNION EUROPEA - FONDO EUROPEO DE DESARROLLO REGIONAL

Área Personal

Safe and effective vaccine against Clostridium perfringens in poultry